Not every stock can be a winner, and last week proved that even large-cap names aren't immune to serious selloffs. If you're holding any of these ten stocks, you probably noticed some red in your portfolio between November 17 and November 21.

The Biggest Losers

AECOM (ACM) took the crown for worst performance, plummeting 21.92% after the infrastructure consulting firm missed Wall Street's expectations for fourth-quarter sales. Making matters worse, several analysts responded by cutting their price targets on the stock.

Sandisk Corporation (SNDK) wasn't far behind, dropping 20.95% for the week. The decline appears to be a momentum reversal, with the stock pulling back after recent gains.

Bloom Energy Corporation (BE) fell 15.99% during the period, while Chinese electric vehicle maker XPeng Inc. (XPEV) slid 12.69% after reporting third-quarter sales that came in below analyst estimates.

Chip Stocks Hit the Brakes

The semiconductor sector had a particularly rough week, with multiple chip stocks reversing course after an earlier rally driven by NVIDIA momentum. Advanced Micro Devices, Inc. (AMD) slumped 16.09%, while Micron Technology, Inc. (MU) dropped 15.99%. Both stocks had benefited from the broader chip sector enthusiasm, but last week's action showed that what goes up can definitely come down.

More Earnings Disappointments

Veeva Systems Inc. (VEEV) decreased 16.28% following its third-quarter earnings report. The life sciences software company also faced multiple analyst downgrades, with several firms lowering their price forecasts.

Jacobs Solutions Inc. (J) fell 16.20% after reporting its fourth-quarter results, which similarly prompted multiple analysts to reduce their price targets on the engineering and consulting stock.

Space and Crypto Take Hits

AST SpaceMobile, Inc. (ASTS) dropped 15.09% despite announcing that its U.S.-licensed BlueBird 6 satellite is scheduled to launch on December 15 from the Satish Dhawan Space Center in India. Sometimes even positive news can't stem the tide.

Coinbase Global, Inc. (COIN) rounded out the top ten losers with a 12.45% decline. Goldman Sachs analyst James Yaro maintained a neutral rating on the cryptocurrency exchange but cut his price target significantly, from $368 down to $314. That's a nearly 15% reduction in the target price, which doesn't exactly inspire confidence.

What It Means

These losses reflect a mix of company-specific issues—missed earnings, disappointing guidance—and broader sector rotations. The chip stock reversal is particularly notable given how hot semiconductors have been this year. When momentum shifts, it can shift fast, and large-cap status offers no protection from market sentiment turning negative.

If any of these stocks are sitting in your portfolio, it might be worth revisiting your thesis to see if the fundamental story has changed or if this is just short-term noise.