PainReform Ltd. (PRFX) shares jumped sharply in Friday's premarket session, posting a 27.4% gain to $1.02. The catalyst? The company announced it's changing its name as part of a broader expansion into diversified healthcare and AI-driven energy platforms. It's one of those corporate rebrand moments that investors seem to think signals bigger things ahead.
But PainReform wasn't alone in making waves before the opening bell. Plenty of other stocks were making notable moves, with some continuing their momentum from Thursday and others rapidly reversing course. Here's what happened across the premarket landscape.
The Big Winners
Acco Group Holdings Limited (ACCL) absolutely exploded, gaining 219.4% to $9.40 in premarket trading. That's the kind of move that makes you wonder what you missed while you were sleeping.
Venus Concept Inc. (VERO) rose 72.2% to $2.48, posting one of the session's more dramatic gains without an immediately obvious catalyst in the headlines.
Jaguar Health, Inc. (JAGX) climbed 41.3% to $1.08 after the company's unit entered into a license agreement with Woodward Specialty. License deals can unlock new revenue streams, and investors appeared optimistic about this one.
ImmunityBio, Inc. (IBRX) gained another 22.8% to $4.85 after already jumping over 30% on Thursday. The momentum continued after the company announced preliminary net product revenue for Anktiva reached approximately $113 million for fiscal 2025, reflecting a remarkable 700% increase year-over-year. That's not a typo—seven hundred percent. Those are the kinds of numbers that get biotech investors very excited.
OneMedNet Corporation (ONMD) rose 14.2% to $0.9711, bouncing back after falling 22% on Thursday. Sometimes stocks just need a breather before finding buyers again.
Brand Engagement Network, Inc. (BNAI) gained 13.8% to $6.50 in premarket action, continuing to build on recent strength.
Springview Holdings Ltd (SPHL) rose 13.4% to $19.75, which might seem modest until you remember the stock jumped 657% on Thursday. Yes, 657%. Even a "small" gain on top of that kind of move represents serious dollar amounts.
Creative Global Technology Holdings Limited (CGTL) gained 10.7% to $4.22 after already jumping 52% on Thursday. Momentum breeds momentum, at least until it doesn't.
Kopin Corporation (KOPN) gained 8.1% to $3.20 in premarket trading, rounding out the gainers list with a solid but comparatively measured advance.
The Pullback Brigade
Not everyone was having a good morning. Several stocks that had monster days on Thursday started giving back some of those gains.
Callan JMB Inc. (CJMB) fell 20.7% to $3.33 in premarket trading. The stock had jumped 275% on Thursday after announcing it signed a strategic teaming agreement with Biostax Corp d/b/a Attune Biotech to provide comprehensive federal oversight services. Apparently some investors decided that was a good time to take profits.
Erayak Power Solution Group Inc. (RAYA) fell 18.3% to $3.21 after jumping 18% on Thursday. Quick up, quick down—that's often how volatile small caps trade.
TryHard Holdings Limited (THH) fell 16.4% to $6.35 in premarket trading. The stock had already dipped 76% on Thursday after the company announced it entered into a Memorandum of Cooperation with STAR PARTY HK LIMITED to explore the establishment of a joint venture in Japan, potentially affecting investor sentiment. When a stock drops 76% and then drops another 16%, you know something has seriously rattled confidence.
iOThree Limited (IOTR) shares dipped 15% to $2.56 in premarket trading without a clear catalyst for the decline.
NOVONIX Limited (NVX) dipped 14% to $1.17 in premarket action, continuing its recent struggles.
Moolec Science SA (MLEC) tumbled 13.1% to $6.69 after jumping 118% on Thursday. When a stock more than doubles in a day, a pullback isn't exactly shocking.
High Roller Technologies, Inc. (ROLR) declined 12.9% to $20.64. The stock had jumped 25% on Thursday after the company announced it signed a non-binding Letter of Intent with Lines.com. Non-binding agreements sometimes generate initial enthusiasm that fades once investors read the fine print.
Bonk, Inc. (BNKK) fell 10.4% to $3.55 in premarket trading. Bonk shares had jumped over 42% on Thursday after the company announced it was acquired by TSX Venture Exchange. Even acquisition news doesn't guarantee sustained gains.
J B Hunt Transport Services Inc (JBHT) fell 4.2% to $197.86 in premarket trading as the company reported mixed financial results for the fourth quarter. Mixed results tend to disappoint investors who were hoping for clear strength.
QXO Inc (QXO) dipped 3.5% to $24.14 after announcing a $750 million common stock offering and reporting preliminary fourth-quarter net sales of $2.19 billion. Stock offerings can dilute existing shareholders, so it's not surprising to see some pressure on the shares.
The premarket session once again reminded us that momentum can be fleeting, especially in smaller, more volatile names. Thursday's heroes can quickly become Friday's faders, and vice versa. For traders watching these moves, the key is understanding which catalysts have staying power and which are just brief bursts of excitement.
