With U.S. stock futures pointing lower Wednesday morning, a handful of companies are poised to grab investor attention today, led by a trio of banking giants reporting quarterly results.

Banking Earnings Take Center Stage

Wall Street is expecting Bank of America Corp (BAC) to report quarterly earnings of 96 cents per share on revenue of $27.87 billion before the opening bell, according to data from Benzinga Pro. Bank of America shares edged down 0.1% to $54.51 in after-hours trading.

Meanwhile, analysts are projecting Citigroup Inc (C) to post quarterly earnings at $1.68 per share on revenue of $20.53 billion. The company will release its results before the markets open. Citigroup shares slipped 0.1% to $116.15 in after-hours trading.

Rounding out the banking trio, analysts expect Wells Fargo & Co (WFC) to deliver quarterly earnings of $1.67 per share on revenue of $21.65 billion before the opening bell. Wells Fargo shares dipped 0.2% to $93.38 in after-hours trading.

Biotech and Pharma Make Waves

TG Therapeutics, Inc. (TGTX) released preliminary fourth quarter revenue estimates and provided an optimistic outlook for 2026. The company said it expects Briumvi U.S. net product revenue to reach approximately $182 million for the fourth quarter and $594 million for the full year of 2025, with total global full year 2025 revenue hitting approximately $616 million.

Gelteq Ltd. (GELS) reported positive preclinical results for its cannabinoid oral gel delivery platform, sending shares soaring 69.3% to $1.41 in after-hours trading.