AbbVie (AbbVie (ABBV)) shares ticked up slightly on Friday after the company dropped some impressive long-term data at the European Hematology Association (EHA) 2026 Congress. The news centers on its venetoclax-based therapy for chronic lymphocytic leukemia (CLL), and the numbers are the kind that make oncologists sit up and take notice.
The data comes from the Phase 3 CLL14 trial, which compared a fixed-duration combo of venetoclax plus obinutuzumab against chlorambucil plus obinutuzumab in previously untreated CLL patients who also had other medical conditions. That's a tough patient population, but the results suggest the venetoclax combo keeps the disease at bay for a very long time.
After a median follow-up of 9.2 years, patients on venetoclax plus obinutuzumab had a median progression-free survival (PFS) of 6.4 years, compared to just 3.2 years for the control group. That's more than double. And the median time to next treatment (TTNT) was 7.6 years, meaning most patients didn't need another therapy for over seven and a half years. That's a big deal for a fixed-duration regimen—patients get a finite course of treatment and then stay in remission for years.
The nine-year analysis also reinforced the safety profile of the combo, with no new red flags. AbbVie is clearly betting that this kind of long-term data will solidify venetoclax's position in the CLL treatment landscape.













