So here's a classic biotech story: a company needs money to develop its drugs, so it sells more stock. Investors who already own shares often don't love that, because it dilutes their ownership. That's what's happening with Candel Therapeutics, Inc. (CADL) on Friday.
The stock is down in premarket trading after the company announced the pricing of a public offering. The plan is to use the cash to get ready to launch its lead cancer therapy and to keep funding clinical trials. It's a necessary step for a development-stage biotech, but it's rarely a popular one with shareholders in the short term.
The Equity Raise
Candel priced an underwritten public offering of around 18.35 million shares at $5.45 per share. That should bring in about $100 million before expenses, and the deal is expected to close around February 23.
Where's the money going? A big chunk is earmarked for "launch readiness" for the company's lead product candidate, a viral immunotherapy called aglatimagene besadenovec (or CAN-2409, which is much easier to type). The rest will help cover ongoing development costs, particularly for a phase 3 trial in non-small cell lung cancer (NSCLC). In short, they're raising cash to try to turn their science into a real product.
What's CAN-2409?
This is the therapy Candel is betting on. The company recently presented data at a medical meeting showing that in a phase 3 trial for intermediate-to-high-risk localized prostate cancer, CAN-2409 demonstrated a statistically significant improvement in prostate cancer-specific disease-free survival. The hazard ratio was 0.62, which is a fancy way of saying the risk of the cancer progressing or causing death was reduced. The effect was seen with different types of radiation therapy used alongside it.
So there's promising data here, which is presumably why the company is gearing up for a potential launch and why it needs the cash to do so. Developing and commercializing drugs is expensive.












